Rodinia – Fertility Tests

Description

Rodinia is a new test that screens for genetic changes (mutations) associated with infertility. By identifying the genetic cause of infertility, your healthcare provider will be able to take informed and accurate decisions on the best clinical management for you, which will help increase your chances of conceiving.

Rodinia is suitable for couples or individuals experiencing pregnancy delay, young people with a suspected disorder of sex development and people with family history of infertility

WHAT IS INFERTILITY?

Infertility is the inability to achieve and maintain a pregnancy and is considered a major disease of the reproductive system. Infertility aff­ects approximately 1 in 6 couples worldwide. In couples experiencing pregnancy delay, male infertility accounts for about 35% and female infertility for about 45% of the cases.

The remaining cases are caused by a combination of male and female factor. 10-15% of men and women have genetic changes associated with infertility. Infertility genetic testing can identify these mutations, providing your healthcare provider with invaluable knowledge that will help them choose the best treatment plan for you.

WHY CHOOSE Rodinia?

Rodinia provides your healthcare provider with valuable genetic insight that could improve your chances of achieving pregnancy:

• Identifies infertility-causing genetic changes
• Provides deep insight that cannot be obtained with non-genetic tests
• Guides your doctor to find the best therapy for you, based on the information provided
• Uses painless and non-invasive collection method
• Delivers time-sensitive and cost-eff­ective genetic information
• Painless sample collection using a Buccal Cheek Swab – can be carried out in the comfort of your own home
• Results within 21 – 28 working days of sample arriving in the laboratory

We always recommend that you discuss your Test Results with your Healthcare Professional

HOW DOES Rodinia HELP ME?

• Identifies the genetic cause for infertility
• Enables accurate prognosis
• Assists your doctor in deciding the most optimal treatment for you
• Increases the chances of successful pregnancy
• Informs your doctor of potential complications from treatment, such as ovarian hyperstimulation syndrome
• Informs you and your doctor early if interventions are beneficial

WHO IS Rodinia FOR?

• Couples or individuals experiencing delay in conceiving
• Women with irregular or absent menstruation
• Men with low sperm count, irregular sperm form or movement
• Individuals with external characteristics indicating a syndrome associated with sex development
• Couples or individuals that will undergo assisted reproductive technology (ART) treatment
• Candidates for sperm or oocyte donation
• Individuals with family history of infertility

HOW CAN INFERTILITY GENETIC TESTING IMPROVE PROGNOSIS?

By identifying the genetic cause of infertility, genetic testing can lead to a more personalized clinical management, and assist in establishing the most fitting fertility treatment for each individual or couple.

In men with azoospermia, genetic testing of the Y chromosome is recommended by the American Society for Reproductive Medicine, as it can identify which men have a chance of recovering sperm through testicular sperm extraction*.

In women with primary ovarian insufficiency, genetic testing provides early identification which is invaluable as egg harvesting and cryopreservation at a young age can be performed to preserve fertility

*Practice Committee of the American Society for Reproductive Medicine. Diagnostic evaluation of the infertile male: a committee opinion (2015)

WHAT DOES Rodinia TEST FOR?

Rodinia off­ers a female and a male infertility panel which detect numerous genetic mutations associated with infertility. Both panels also test for whole, partial and mosaic* sex chromosome changes which can cause fertility problems.

*Mosaicism refers to the condition of having two or more sets of cells that di‑er genetically from one another

FEMALE INFERTILITY PANEL (55 GENES) – £499

Includes testing of the X chromosomes, and disorders such as primary ovarian insufficiency, polycystic ovary syndrome, hypogonadotropic hypogonadism and ovarian hyperstimulation syndrome

MALE INFERTILITY PANEL (40 GENES) – £499

Includes testing of X and Y chromosomes, including Y-chromosome microdeletions, and disorders such as hypogonadotropic hypogonadism, like Kallmann syndrome

ADD ON PANEL – £159

Haemophilia and Thrombosis panel (21 mutations) Haemophilia and Thrombosis panel is available upon request and could be beneficial to couples or individuals with more than one miscarriage

COUPLES PANEL – £795

Includes both Female & Male Infertility Panels

COUPLES ADD ON PANEL – £239

Haemophilia and Thrombosis panel (21 mutations) for both partners

WHAT CAN I DO AFTER Rodinia?

Doctors use various methods to treat infertility. Based on Rodinia’s results, doctors can identify the most beneficial treatment for you taking into consideration potential complications

• Lifestyle changes eg. Maintain a healthy body weight, quit smoking, avoid alcohol
• Medication eg. Ovulation induction drugs, hormones
• Surgical procedure eg. Testicular sperm extraction
• Cryopreservation eg. Oocyte harvesting at a young age to preserve fertility
• Assisted reproductive technology eg. In vitro fertilization

Please click here to view brochure     

Please click here to view infertility panel